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Genetic disorders should be the focus of CRISPR gene editing trials

5 December 2018

Genetic disorders should be the focus of CRISPR gene editing trials

Science Photo Library – ZEPHYR

He Jiankui tried to use to , but many believe the most-compelling case for gene editing before birth is to prevent genetic disorders.

Most disorders caused by mutations in a single gene, such as cystic fibrosis, can already be prevented. One way of doing this is to screen IVF embryos for harmful mutations before implanting them.

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However, such preimplantation genetic diagnosis has limitations, particularly when you only need to inherit the mutation from one parent to …

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